一、个人简介
张纯，女，1989年03月出生，博士、助理研究员，中国化学会会员。
主要经历：
2008.09-2012.06，河北科技师范学院，化学专业，理学学士
2012.09-2018.06，吉林大学，物理化学专业，理学博士
2018.07-2020.07，南京大学，有机化学专业，博士后
2020.08-至今，江南大学，生命科学与健康工程学院，助理研究员
二、研究领域
1.活性分子与蛋白酪氨酸磷酸酶的作用机制模拟研究。
2.蛋白酪氨酸磷酸酶调节剂的光物理性质研究。
1.近红外/红外（双光子）荧光探针分子在生物体内重金属离子（Pd2+和Hg2+）和重要生物酶（β-galactosidase和CYP1A）的荧光成像检测的理论设计研究。
2.用于复杂生物体系的新型生物正交试剂的理论研究。
3.天然[6+4]环加成酶选择性以及反应机理的动力学理论研究。
三、学术成果
（一）代表性论文
1.Chun Zhang, Yv-Ting Yang, Xue Yan, Yi-Tao Sun, An-Dong Shao, Si-Nuo Gao, Yu-Bo Zhou, Ai-Min Ren*, Jia Li*, Wen-Long Wang*.A study on optical properties for various hot drug molecules by 2020. New Journal of Chemistry, 2023, Accepted.
2.Ranran Wang,Chun Zhang（共一）, Yuan Chen, Wang Xie, Jianmin Jiao, Yong Liang, Leyong Wang, and Juli Jiang*.Locally Rotated Chiral Molecular Tiara with Reversible CPL Emissions. Advanced Optical Materials, 2023, 2202913 (1 to 6).
3.Wenyuan Xu, Zhuzhou Shao, Cheng Tang,Chun Zhang*, Yinghan Chen,* Yong Liang*.Fluorogenic sydnonimine probes for orthogonal labeling. Organic Biomolecular Chemistry, 2022,20, 5953-5957.
4.Chun Zhang, Yi-Tao Sun, Li-Xin Gao, Bo Feng, Xue Yan, Xue-Hui Guo,Ai-Min Ren*, Yu-Bo Zhou, Jia Li*, Wen-Long Wang*.Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1. Physical Chemistry Chemical Physics, 2022, 24, 861-874.
5.Xin Wang,Chun Zhang（共一）, Yaoyukun Jiang, Wen Wang, Yuan Zhou, Yu Chen, Bo Zhang, Ren Xiang Tan, Hui Ming Ge*, Zhongyue J. Yang*, Yong Liang*.Influence of Water and Enzyme on the Post-Transition State Bifurcation of NgnD-Catalyzed Ambimodal [6+4]/[4+2] Cycloaddition.Journal of American Chemical Society, 2021, 143, 21003−21009.
6.Chun Zhang, Ai-Min Ren, Jing-Fu Guo, Dan Wang, Li-Ying Yu. Theoretical prediction and investigation of 1,8-naphthalimide-based two-photon fluorescent probes for detecting Cytochrome P450 1A with separated fluorescence signal. Physical Chemistry Chemical Physics, 2018, 20, 13290-13305.
7.Chun Zhang, Xin Wang, Peiyuan Yu, Yong Liang*. The Dynamical Trajectory study for a kind of Transannular [6 + 4] and Ambimodal Cycloaddition in the Biosynthesis of Heronamide. Journal of Organic Chemistry. 2020, 85, 9440−9445.
8. Zhuzhou Shao,Chun Zhang（共一）, Xiaohua Zhu, Yajun Wang, Wenyuan Xu, Yu Chen, Xiaoming Wang, Hailiang Zhu, Yong Liang*. Design of a 1,8-naphthalimide-based OFF-ON type biorthogonal reagent for fluorescent imaging in live cells. Chinese Chemical Letters, 2019, 30, 2169−2172.
9.Chun Zhang, Lu-Yi Zou, Dan Wang, Li Zhang, Ai-Min Ren*. A theoretical investigation and design of fluorescent probes with large two-photon absorption cross-sections and dual signaling behavior for mercury ions in biological system. Journal of Photochemistry and Photobiology A-Chemistry, 2017, 332, 440−452.
10.Chun Zhang, Dan Wang, Li Zhang, Jing-Fu Guo, Ai-Min Ren*. Theoretical investigation and design of two-photon fluorescent probes for visualizingβ-galactosidase activity in living cells. RSC Advances, 2016, 6, 70960−70971.
11.Chun Zhang, Jing-Fu Guo, Ai-Min Ren*, Dan Wang. A theoretical investigation on two-photon absorption and fluorescent properties of coumarin-based derivatives for Pd2+ detection. RSC Advances, 2017, 7, 49505−49517.
四、联系方式
通讯地址：江苏省无锡市蠡湖大道1800号江南大学生命科学与健康工程学院
邮编：214122
邮箱：zhangchun@jiangnan.edu.cn
【以上资料更新日期】：2023年4月
