一、个人简介
邵安东,男,1989年11月出生,博士、副研究员。
主要经历:
2007.09-2011.06,华东理工大学,应用化学专业,工学学士
2011.09-2016.06,华东理工大学,应用化学专业,工学博士(导师:朱为宏教授)
2016.08-2020.09,美国Wistar研究所(NIH/NCI),博士后
2020.11-2022.01,江南大学,药学院,副研究员
2022.02-至今,江南大学,生命科学与健康工程学院,副研究员
二、研究领域
近年来主要从事光化学和生物医药的研究,围绕“AIE荧光生物成像——药物缓释和靶向治疗——诊疗一体化”的思路展开了一系列创新性的科学研究。已经在国际学术刊物上发表SCI论文14篇,专利2项。其中以第一作者或共同一作在Angew. Chem. Int. Ed., Chem. Sci., Adv. Mater.,J. Med. Chem., Mol. Cancer Ther.等期刊发表论文9篇,他引700余次,1篇入选ESI高被引论文。
三、学术成果
(一)代表性项目
1.国家自然科学基金-青年(2022-2024),主持
2.江苏省自然科学基金-青年(2021-2024),主持
3.第69批全国博士后面上资助(2021-2022),主持
4.中央高校自主科研计划青年基金(2021-2022),主持
(二)代表性论文
1.Andong Shao, Qin Xu, Chang Won Kang, Christopher F. Cain, Avery Lee, Chih-Hang Anthony Tang, Juan R. Del Valle, Chih-Chi Andrew Hu, An IRE-1-targeting caged prodrug with ER stress-inducing and XBP-1s-inhibiting activities for cancer therapy,Mol.Pharm.,2022, Accepted.
2.Andong Shao, Qin Xu, Walker T. Spalek, Christopher F. Cain, Chang Won Kang, Chih-Hang Anthony Tang, Juan R. Del Valle, Chih-Chi Andrew Hu, Development of Tumor-specific IRE-1 Inhibitors for B cell Cancer Therapy,Mol.Cancer Ther.,2020,19, 2432.
3.Andong Shao, Chang Won Kang, Chih-Hang Anthony Tang, Christopher F. Cain, Qin Xu, Claire M. Phoumyvong, Juan R. Del Valle, Chih-Chi Andrew Hu, Structural Tailoring of a Novel Fluorescent IRE‑1 RNase Inhibitor to Precisely Control Its Activity,J. Med. Chem.,2019,62, 5404.
4.Yan Tang,Andong Shao#, Jun Cao, Hui Li, Qiang Li, Meiying Zeng, Ming Liu, Yingsheng Cheng, Weihong Zhu, cNGR-based Synergistic-targeted NIR Fluorescent Probe for Tracing and Bioimaging of Pancreatic Ductal Adenocarcinoma,Science China Chemistry,2018,61, 184.
5.Meiying Zeng,Andong Shao#, Hui Li, Yan Tang, Qiang Li, Zhiqian Guo, Chungen Wu, Yingsheng Cheng, He Tian, Weihong Zhu, Peptide Receptor-Targeted Fluorescent Probe: Visualization and Discrimination between Chronic and Acute Ulcerative Colitis,ACS Applied Materials & Interfaces,2017,9, 13029.
6.Yongsheng Li,Andong Shao#,Yao Wang, Ju Mei, Dechao Niu, Jinlou Gu, Ping Shi, Weihong Zhu, He Tian, Jianlin Shi, Morphology Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging,Adv. Mater.,2016,28, 3187.
7.Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian, Guo, Shiqin Zhu, Jin Guo, Ping Shi, Tony D. James, He Tian, Weihong Zhu, Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy: Shape-Specific Effects,Angew. Chem. Int. Ed.2015, 54, 7275.
8.Andong Shao, Zhiqian, Guo, Shaojia Zhu, Shiqin Zhu, Ping Shi, He Tian, Weihong Zhu, Insight into Aggregation-induced Emission Characteristics of Red-emissive Quinolinemalononitrile by Cell Tracking and Real-time Trypsin Detection,Chem. Sci.2014,5, 1383.
四、联系方式
通讯地址:江苏省无锡市蠡湖大道1800号江南大学生命科学与健康工程学院
邮编:214122
邮箱:adshao@jiangnan.edu.cn
【以上资料更新日期】:2022年2月