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Professor
Dr. Jian-Song Sun
By:The School of Life Science and Health Engineering    Date:2024-03-14 16:07:38    View:25

Affiliation: School of Life Science and Health Engineering, Jiangnan University

Mail Address: Room 711, Synergestic Innovation Center, Jiangnan University, No. 1800 Li Lake Avenue, Binhu District, Wuxi

Phone: 15070891912

Email: sunjiansong@jiangnan.edu.cn

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I. Education

Ph.D. in Organic Chemistry/Glycochemistry (2000-2005)

Jointly trained by Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, and Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Advisors: Prof. Biao Yu and Prof. Xiu-Wen Han.

B.Sc. in Chemistry Education (1996-2000)

Qufu Normal University

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II. Research Experience

Professor(Level III), PhD Supervisor (2022-Present)

School of Life Science and Health Engineering, Jiangnan University

Research Interests: Development of novel glycosylation methods and efficient synthesis of complex natural active glycosylated compounds.

Research Fellow, PhD Supervisor, Director (2014-2022)

National Research Center for Carbohydrate Synthesis (Jiangxi Normal University)

Research Interests: As above.

Associate Researcher, Master's Supervisor (2007-2014)

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

Research Interests: As above.

Postdoctoral Fellow, Humboldt Scholar (2006-2007)

University of Konstanz, Germany. Collaborating Professor: Richard R. Schmidt.

Research Interests: Synthesis study of lipid A of LTA.

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III. Honors and Awards

1.Ogawa Young Investigator Award (2022)

2. Second Prize, Jiangxi Provincial Natural Science Award (2022)

3. "Zhang Shuzheng Glycoscience Award - Outstanding Young Scientist Award" (2019)

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IV. Represent Publications

1.Hui Liu,* Zhi-Fen Liang, Han-Jian Liu, Jin-Xi Liao, Li-Jun Zhong, Yuan-Hong Tu, Qing-Ju Zhang, Bin Xiong,Jian-Song Sun*ortho-Methoxycarbonylethynylphenyl thioglycosides (MCEPTs): versatile glycosyl donors enabled by electron-withdrawing substituents and catalyzed by gold(I) and Cu(II) complex.J. Am. Chem. Soc.2023,145, 3682-3695.

2.Si-Yu Zhou, Xin-Ping Hu, Hui-Juan Liu, Qing-Ju Zhang, Jin-Xi Liao*, Yuan-Hong Tu,Jian-Song Sun* 8-(Methyltosylaminoethynyl)-1-naphthyl(MTAEN) glycosides: potent donors in glycosides synthesis.Org. Lett.2022,24, 653-657.

3.Zhi-Yong Zeng, Jin-Xi Liao, Zhen-Ni Hu, De-Yong Liu, Qing-Ju Zhang,Jian-Song Sun* Chemical Synthesis of Quillaic Acid, the Aglycone of QS-21.Org. Chem. Front.2021,8, 748-753.

4.Zhi-Yong Zeng, Jin-Xi Liao, Zhen-Ni Hu, De-Yong Liu, Qing-Ju Zhang,Jian-Song Sun*. Synthetic Investigation toward QS-21 Analogues.Org. Lett.2020,22, 8613-8617.

5.Hui Liu, Thomas Hansen, Si-Yu Zhou, Guo-En Wen, Xu-Xue Liu, Qing-Ju Zhang, Jeroen D. C. Codee,* Richard R. Schmidt,Jian-Song Sun*. Dual-Participation Protecting Group Solves the Anomeric Stereocontrol Problems in Glycosylation Reactions.Org. Lett.2019,21, 8713-8717.

6.Jian Chen, Thomas Hansen, Qing-Ju Zhang, De-Yong Liu, Yao Sun, Hao Yan, Jeroen D. C. Codee, Richard R. Schmidt,*Jian-Song Sun*. 1-Picolinyl-5-azido Thiosialosides: Versatile Donors for the Stereoselective Construction of Sialyl Linkages.Angew. Chem. Int. Ed.2019,58, 17000-17008.

7.Hui Liu, Si-Yu Zhou, Guo-En Wen, Xu-Xue Liu, De-Yong Liu, Qing-Ju Zhang, Richard R. Schmidt,Jian-Song Sun*. The 2,2-Dimethyl-2-(ortho-Nitrophenyl)acetyl (DMNPA) Group: A Novel Protecting Group in Carbohydrate Chemistry.Org. Lett.2019,21, 8049-8052.

8.Yang Hu, Ke Yu, Li-Li Shi, Lei Liu, Jing-Jing Sui, De-Yong Liu, Bin Xiong,Jian-Song Sun*.o-(p-Methoxyphenylethynyl)phenyl Glycosides: Versatile New Glycosylation Donors for the Highly Efficient Construction of Glycosidic Linkages.J. Am. Chem. Soc.2017,139, 12736-12744.

9.Hui Liu, Jin-Xi Liao, Yang Hu, Yuan-Hong Tu,Jian-Song Sun*. A Highly Efficient Approach to Construct (epi)-Podophyllotoxin-4-O-glycosidic Linkages as well as Its Application in Concise Synthesis of Etoposide and Teniposide.Org. Lett.2016,18, 1294-1297.

10.Jun Yu,Jiansong Sun*, Yiming Niu, Rongyao Li, Jinxi Liao, Fuyi Zhang, Biao Yu*. Synthesis Access Toward the Diverse Ginsenosides.Chem. Sci.2013,4, 3899-3905.

11.Jun Yu,Jiansong Sun*,Biao Yu*. Construction of Interglycosidic N-O Linkages via Direct Glycosylation of Sugar Oximes.Org. Lett.2012,14, 4022-4025.

12.Yan Li,Jiansong Sun*, Biao Yu*. Efficient Synthesis of Lupane-Type Saponins via Gold(I)-Catalyzed Glycosylation with Glycosylortho-Alkynylbenzoates as Donors.Org. Lett.2011,13, 5508-5511.

13.Qingju Zhang,Jiansong Sun*, Yugen Zhu, Fuyi Zhang, Biao Yu*. An Efficient Approach to the Synthesis of Nucleosides: Gold(I)-Catalyzed N-Glycosylation of Pyrimidines and Purines with Glycosylortho-Alkynyl Benzoates.Angew. Chem. Int. Ed.2011,50, 4933-4936.

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