Education

Research Experience and Skills

·Biomedical materials for tissue engineering

Biomedical materials with different functions are designed and prepared for tissue engineering, such as blood vessel regeneration, nerve repair, dura grafts and so on. These materials are made of natural polysaccharides or protein to mimic extracellular matrix.

·Controlled drug delivery system based on nanoparticles

“Smart” drug delivery system based on nanoparticles were synthesized and applied in the antibacterial and anticancer studies. By conjugation of functional moieties on the surface of nanoparticles, the nanomedicine can target transport and controlled release of drugs.

Typical Publications

1.Juan Zhou,Hong Wang, Hao Chen, Yan Ling, Ziqi Xi, Mingting Lv, Jinghua Chen*. pH-responsive nanocomposite hydrogel for simultaneous prevention of postoperative adhesion and tumor recurrence,Acta Biomaterialia, 2023, 158, 228-238. (IF 10.633)

2.Liangyu Guo, HaoChen, YuanliLi, Juan Zhou*, Jinghua Chen*.Biocompatible scaffolds constructed by chondroitin sulfate microspheres conjugated 3D-printed frameworks for bone repair,Carbohydrate Polymers, 2022, 299, 120188. (IF 10.723)

3.Yiting Shen, Mingyu Wang, Hong Wang, Juan Zhou*, Jinghua Chen*. Multifunctional Human Serum Albumin Fusion Protein as a Docetaxel Nanocarrier for Chemo-photothermal Synergetic Therapy of Ovarian Cancer,ACS Applied Materials & Interfaces, 2022, 14, 17, 19907–19917. (IF 10.383)

4.Li Zhang, Hong Wang, Yiting Shen, Ying Sun, Juan Zhou *, Jinghua Chen *.Glycosaminoglycans immobilized core-shell gold mesoporous silica nanoparticles for synergetic chemo-photothermal therapy of cancer cells,Materials Letters, 2022, 308, 131113

5.Li Zhang, Yuting Zhou, Dandan Su, Shangyan Wu, Juan Zhou*, Jinghua Chen*. Injectable, self-healing and pH responsive stem cell factor loaded collagen hydrogel as a dynamic bioadhesive dressing for diabetic wound repair,Journal of Materials Chemistry B, 2021, 9, 5887-5897. IF (7.571)

6.Juan Zhou, Yanzhe Wu, Xihe Zhang, Jiahui Lai, Yuanli Li, Jian Xing, Liping Teng*, and Jinghua Chen*. Enzyme Catalyzed Hydrogel as Versatile Bioadhesive for Tissue Wound Hemostasis, Bonding, and Continuous Repair,Biomacromolecules2021, 22, 4, 1346-1356. (IF 6.978)

7.Huan Xu*, Juan Zhou, Karin Odelius, Zhijun Guo, Xin Guan, and Minna Hakkarainen*, Nanostructured Phase Morphology of a Biobased Copolymer for Tough and UV-Resistant Polylactide,ACS Appl. Polym. Mater.2021, 3, 4, 1973-1982.

8.Mingyu Wang, Li Zhang, Yanfei Cai, Yang Yang, Lipeng Qiu, Yiting Shen, Jian Jin, Juan Zhou*, and Jinghua Chen*, Bioengineered Human Serum Albumin Fusion Protein as Target/Enzyme/pH Three-Stage Propulsive Drug Vehicle for Tumor Therapy.ACS Nano2020, 14, 12, 17405-17418. (IF 18.027)

9.Juan Zhou, Yuning Han, Yang Yang, Li Zhang, Hong Wang, Yiting Shen, Jiahui Lai, and Jinghua Chen*. Phospholipid-Decorated Glycogen Nanoparticles for Stimuli-Responsive Drug Release and Synergetic Chemophotothermal Therapy of Hepatocellular Carcinoma.ACS Applied Materials & Interfaces2020, 12, 20, 23311-23322. (IF 10.383)

10.Yuning Han, Bin Hu, Mingyu Wang, Yang Yang, Li Zhang, Juan Zhou* and Jinghua Chen*. pH-Sensitive Tumor-Targeted Hyperbranched System Based on Glycogen Nanoparticles for Liver Cancer Therapy.Applied Materials Today, 2020, 18, 100521. (IF 8.633)

11.Juan Zhou, Mingyu Wang, Yuning Han, Jiahui Lai, and Jinghua Chen*. Multistage-Targeted Gold/Mesoporous Silica Nanocomposite Hydrogel as in Situ Injectable Drug Release System for Chemophotothermal Synergistic Cancer Therapy.ACS Applied Bio Materials, 2020, 3, 1, 421-431.

12.Xihe Zhang, Juan Zhou*, Huiyan Ying, Yuting Zhou, Jiahui Lai, and Jinghua Chen*. Glycogen as a Cross-Linking Agent of Collagen and Nanohydroxyapatite to Form Hydrogels for bMSC Differentiation.ACS Sustainable Chemistry & Engineering, 2020, 8, 4, 2106-2114. (IF 9.224)

13.Huiyan Ying, Juan Zhou*, Mingyu Wang, Dandan Su, Qiaoqiao Ma, Guozhong Lv and Jinghua Chen*. In Situ Formed Collagen-Hyaluronic Acid Hydrogel as Biomimetic Dressing for Promoting Spontaneous Wound Healing.Materials Science and Engineering: C, 2019, 101, 487-498. I 8.457

14.Dandan Su, Juan Zhou*, Kamel S.Ahmed, Qiaoqiao Ma, Guozhong Lv and Jinghua Chen*. Fabrication and characterization of collagen-heparin-polypyrrole composite conductive film for neural scaffold.International Journal of Biological Macromolecules, 2019, 129, 895-903.

15.Safia Naz, Muhammad Shamoon, Rui Wang, Li Zhang, Juan Zhou* and Jinghua Chen*. Advances in Therapeutic Implications of Inorganic Drug Delivery Nano-Platforms for Cancer.International Journal of Molecular Science, 2019, 20, 965-982.

16.Safia Naz, Mingyu Wang, Yuning Han, Bin Hu, Liping Teng, Juan Zhou*, Huijie Zhang* and Jinghua Chen. Enzyme Responsive Mesoporous Silica Nanoparticles for Tumor Cells and Mitochondria Multistage-Targeted Drug Delivery.International Journal of Nanomedicine, 2019, 14, 2533-2542.

Institutional Service

1.Assistant Dean of School of Pharmaceutical Sciences, 2017-2021

Responsible for arranging international exchange affairs, including joint bachelor-master study program, international joint labratory, etc.

2.Jiangsu "Entrepreneurship and Innovation Program" - PhD in Entrepreneurship and Innovation (World Famous Schools)

3.Excellent graduation Instructor in 2021 (Jiangsu Province Third Prize)

4.The third prize of the National College Student Life Science Competition in 2021;

5.The 17th "Challenge Cup" National College Students Extracurricular Academic Science and Technology Works Competition Jiangsu Province first prize;

6.The third prize of the National College Student Life Science Competition in 2022;

7.Bronze Award of the 7th China College Students “Internet+” Innovation and Entrepreneurship Competition

Contact Information

School of Life Sciences and Health Engineering  Jiangnan University

Lihu Avenue 1800, Wuxi, Jiangsu, China

E-mail:juanzhou@jiangnan.edu.cn

Mobile: +86-15190243587