Education and Experience:
Sep.1991-July 1995, School of biotechnology, Jiangnan University,Bachelor of Engineering;
Aug.1995-July 2009, School of biotechnology, Jiangnan University,Research assistant;
Mar.1999-Apr.2002,School of biotechnology, Jiangnan University, Master of engineering;
Aug.2009-present, School of Life Sciences and Health Engineering, Jiangnan University,Associate professor。
Research fields:
1.Study on the mammalian cell lines for biopharmaceutical production
2.Study on the mechanism of multidrug resistance in tumor
3.Study on the pharmacokinetics and drug quality standard
Selected publications:
[1]Breast cancer resistance protein(BCRP)-containing circulating microvesicles contribute to chemoresistance in breast cancer.Oncology Letters2015,10:3742-8
[2] Crystallization and preliminary X-ray diffraction analysis of an endo-1,4-β-D-glucanase from Aspergillus aculeatus F-50. Acta Cryst.2015, F71: 397-400
[3] Development and characterization of monoclonal antibodies against pancreatic cancer marker hippocalcin-like 1 protein. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 2014, 33: 20-7
[4] A comprehensive screening method for investigating the potential binding targets of doxorubicin based on protein microarray. European Journal of Pharmacology. 2021, online
[5] Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells. Proc Natl Acad Sci USA 2012, 109:16282-7
[6] Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance. Proc Natl Acad Sci USA 2014, 111 : 6389-94
[7] USE OF GENOMIC NW_006880285.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN,United States Patent, US11692204 B2
[8] USE OF GENOMIC NW_006882077.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN,United States Patent, US11732276 B2
[9] USE OF NW_003613638.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEIN,Singapore patent, 11202009389Q
[10] USE OF NW_006882456.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEINS,United States Patent, 11202010741W