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Professor
Dr.Jun Lin
By:The School of Life Science and Health Engineering    Date:2024-03-14 16:06:15    View:25

Name

Jun   Lin

Gender

Male

Date   of birth

1979.1

Professional   Title

Professor

Tel


E-mail

junlin@jiangnan.edu.cn

Education background

2009.12, Ph.D.   Fermentation engineering, Jiangnan University, Wuxi, China.

2000.7,   Bachelor, Biotechnology, Jiangnan University, Wuxi, China.

Professional experience

2022.01-   present, Professor, School of Life Science and Health Engineering, Jiangnan University.

2018.06-2022.01,   Professor, School of Pharmacy, Jiangnan University.

2012.03   -2018.06, PI, Shanghai Institute of Pharmaceutical Industry.

2009.12 -2012.03,   Postdoctoral Fellow, Shanghai Institute of Pharmaceutical Industry.

2002.03-2005.03,   Yantai Medgenn Co., Ltd.

2000.07-2002.03,   Yantai Beer Asahi Co., Ltd.

Research   Interests

New drug research and development, research   in synthetic biology.

Selected   Publications

[1] P. Lin, Z. Chen, J. Lin,   Therapeutic drugs of gout: The progress in target selection, Int J Rheum Dis   (2023) e15022.

[2] P. Lin, D. Zhang, J. Lin,   Clinical Research Progress of BTK Inhibitors in the Treatment of Autoimmune   Diseases, Curr Top Med Chem 23 (2023) 2609-2620.

[3] P. Lin, H.Y. Shi, Y.Y. Lu, J. Lin,   Centella asiatica alleviates psoriasis through JAK/STAT3-mediated   inflammation: An in vitro and in vivo study, J Ethnopharmacol 317 (2023)   116746.

[4] J. Lin, L.Y. Yang, Z.D. Pan,   Identification of Potential Bioactive Compounds from Aspergillus terreus   against HCV NS3 Serine Protease, Chem Biodivers 20(8) (2023) e202300532.

[5] J. Lin, Y.Y. Lu, H.Y. Shi, P.   Lin, Chaga Medicinal Mushroom, Inonotus obliquus (Agaricomycetes),   Polysaccharides Alleviate Photoaging by Regulating Nrf2 Pathway and   Autophagy, Int J Med Mushrooms 25(10) (2023) 49-64.

[6] S. Chen, Z. Chen, L. Lu, Y. Zhao, R.   Zhou, Q. Xie, Y. Shu, J. Lin, X. Yu, Y. Wang, Discovery of novel BTK   PROTACs with improved metabolic stability via linker rigidification strategy,   Eur J Med Chem 255 (2023) 115403.

[7] M. Hong, K. Xiao, P. Lin, J. Lin,   Five Rutaceae family ethanol extracts alleviate H(2)O(2) and LPS-induced   inflammation via NF-κB and JAK-STAT3 pathway in HaCaT cells, Chin J Nat Med   20(12) (2022) 937-947.

[8] B.X. Du, P. Lin, J. Lin, EGCG   and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and   PI3K/AKT/mTOR pathway in human melanoma cells, Chin J Nat Med 20(4) (2022)   290-300.

[9] Y. Zhao, Y. Shu, J. Lin, Z.   Chen, Q. Xie, Y. Bao, L. Lu, N. Sun, Y. Wang, Discovery of novel BTK PROTACs   for B-Cell lymphomas, Eur J Med Chem 225 (2021) 113820.

[10] S. Liu, Y. Da, F. Wang, R. Yan, Y.   Shu, P. Lin, J. Lin, Targeted selective degradation of Bruton’s   tyrosine kinase by PROTACs, Med. Chem. Res. 29(4) (2020) 802-808.

[11] Y. Da, S. Liu, P. Lin, F. Wang, R. Yan,   Y. Shu, J. Lin, Design, synthesis, and biological evaluation of small   molecule PROTACs for potential anticancer effects, Med. Chem. Res. 29(2)   (2020) 334-340.


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