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Dr.Jing Wu
By:The School of Life Science and Health Engineering    Date:2018-10-25 11:01:17    View:25

Jing Wu, Associate Professor

 

School of Pharmaceutical Sciences, Jiangnan University

No. 1800 Lihu Avenue, Wuxi, jiangsu, RPC

E-Mail: wujing@jiangnan.edu.cn

 

Education

May 2013 – Jun. 2014

Postdoc.

Northwestern University, USA

Department of Chemical and Biological Engineering                                                   

Sep. 2003 –Sep.  2008

Ph.D.

 

Jiangnan University, China

School of Biotechnology

 

Sep. 1999 –Jun. 2003

B.S.

Jiangnan University, China

School of Biotechnology

Work Experience

Jan. 2017 - Now

Associate

Professor

Jiangnan University

School of Pharmaceutical Sciences

Sep. 2012 – Dec. 2016

Associate

Professor

Jiangnan University

Wuxi Medical School 

Oct. 2008 – Aug. 2012

Lecturer

Jiangnan University

School of Medicine and Pharmaceutics

Area of Research

1. Production of pharmaceutical intermediates by biotechnology.

2. Enzyme discovery, reconstruction and application.

Research Projects

1. National Natural Science Foundation of China (21576117), Mechanism of metal ions regulating the processivity and fidelity of Y family polymerase Dpo4.

2. National Natural Science Fund Youth Fund (31101229), Molecular modification on the heat / alkali resistance of xylanase from Aspergillus oryzae.

3. the branch project of Chinese High-tech R&D Program(863) (2012AA022 108), Genome engineering improves the production of pharmaceutical proteins by Bacillus subtilis.

4. Key research and development plan of Jiangsu Province (BE2015307), Study on the key technology of microbial preparation of  vitamin C phosphate.

Journal Publications

1. Zhang Q, Yao R, Chen X, Liu L, Xu S, Chen J, Wu J*. Enhancing fructosylated chondroitin production in Escherichia coli K4 by balancing the UDP-precursors. Metab Eng. 2018, 47:314-322.

2. Wang L, Liang C, Wu J*, Liu L, Tyo KEJ. Increased Processivity, Misincorporation, and Nucleotide Incorporation Efficiency in Sulfolobus solfataricus Dpo4 Thumb Domain Mutants. Appl Environ Microbiol. 2017,83(18). pii: e01013-17.

3. Zheng K, Song W, Sun A, Chen X, Liu J, Luo Q, Wu J*. Enzymatic Production of Ascorbic Acid-2-phosphate by Recombinant Acid Phosphatase. J Agric Food Chem. 2017, 65(20):4161-4166.

4.Wu J, Wang H, Yang B, Song W, Liang C, Liu L. Efficient production of (R)-3-TBDMSO glutaric acid methyl monoester by manipulating the substrate pocket of Pseudozyma antarctica lipase B.RSC Adv., 2017, 7, 38264-38272

5. Yun J, Duan F, Liu L, Chen X, Liu J, Luo Q, Wu J*. A selective and sensitive nanosensor for fluorescent detection of specific IgEs to purified allergens in human serum. RSC Adv., 2018,8(7): 3547-3555.

6. Wu J, de Paz A, Zamft BM, Marblestone AH, Boyden ES, Kording KP, Tyo KEJ. DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase. Sci Rep. 2017,7(1):4756.

7.Wang Y, Xu N, Ye C, Liu L, Shi Z, Wu J*. Reconstruction and in silico analysis    of an Actinoplanes sp. SE50/110 genome-scale metabolic model for acarbose production. Front Microbiol. 2015,6:632.

8. Luo Q, Wu J*, Wu M. Enhanced acetoin production by Bacillus amyloliquefaciens through improved acetoin tolerance, Process Biochemistry,2014,49:1223-1230

9. Zhang Y, Li S, Liu L, Wu J*. Acetoin production enhanced by manipulating carbon flux in a newly isolated Bacillus amyloliquefaciens. Bioresour Technol. 2013 ,130: 256-260.

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Technical support: information construction and Management Center

Address: no. 1800, lihu avenue, wuxi, jiangsu, 214122

PC:214122

Contact number:0510-85913623,85913625 

Service mailbox:international@jiangnan.edu.cn